Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.17/912
Título: Impact of RIFLE Classification in Liver Transplantation
Autor: Ferreira, AC
Nolasco, F
Carvalho, D
Sampaio, S
Baptista, A
Pessegueiro, P
Monteiro, E
Mourão, L
Barroso, E
Palavras-chave: Lesão Renal Aguda
Estudos de Follow-Up
Taxa de Filtração Glomerular
Rim
Transplantação de Fígado
Estudos Prospectivos
Terapia de Substituição Renal
Factores de Risco
Taxa de Sobrevivência
Resultado de Tratamento
Data: 2010
Editora: Wiley
Citação: Clin Transplant. 2010 May-Jun;24(3):394-400
Resumo: Acute renal failure (ARF) is common after orthotopic liver transplantation (OLT). The aim of this study was to evaluate the prognostic value of RIFLE classification in the development of CKD, hemodialysis requirement, and mortality. Patients were categorized as risk (R), injury (I) or failure (F) according to renal function at day 1, 7 and 21. Final renal function was classified according to K/DIGO guidelines. We studied 708 OLT recipients, transplanted between September 1992 and March 2007; mean age 44 +/- 12.6 yr, mean follow-up 3.6 yr (28.8% > or = 5 yr). Renal dysfunction before OLT was known in 21.6%. According to the RIFLE classification, ARF occurred in 33.2%: 16.8% were R class, 8.5% I class and 7.9% F class. CKD developed in 45.6%, with stages 4 or 5d in 11.3%. Mortality for R, I and F classes were, respectively, 10.9%, 13.3% and 39.3%. Severity of ARF correlated with development of CKD: stage 3 was associated with all classes of ARF, stages 4 and 5d only with severe ARF. Hemodialysis requirement (23%) and mortality were only correlated with the most severe form of ARF (F class). In conclusion, RIFLE classification is a useful tool to stratify the severity of early ARF providing a prognostic indicator for the risk of CKD occurrence and death.
Peer review: yes
URI: http://hdl.handle.net/10400.17/912
Aparece nas colecções:CHBPT - Artigos
UCI - Artigos

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