Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.17/876
Título: Epilepsy and Cerebral Palsy: Characteristics and Trends in Children Born in 1976 - 1998
Autor: Sellier, E
Uldall, P
Calado, E
Solveig, S
Torrioli, MG
Platt, MJ
Cans, C
Palavras-chave: Epilepsia
Paralisia Cerebral
Factores de Risco
Data: 2012
Editora: Elsevier
Citação: Eur J Paed Neurology. 2012; 16: 48-55
Resumo: Background: Although epilepsy is common in children with cerebral palsy (CP), no data exists on prevalence rates of CP and epilepsy. Aims: To describe epilepsy in children with CP, and to examine the association between epilepsy and neonatal characteristics, associated impairments and CP subtypes. Methods: Data on 9654 children with CP born between 1976 and 1998 and registered in 17 European registers belonging to the SCPE network (Surveillance of Cerebral Palsy in Europe)were analyzed. Results: A total of 3424 (35%) children had a history of epilepsy. Among them, seventy-two percent were on medication at time of registration. Epilepsy was more frequent in children with a dyskinetic or bilateral spastic type and with other associated impairments. The prevalence of CP with epilepsy was 0.69 (99% CI, 0.66e0.72) per 1000 live births and followed a quadratic trend with an increase from 1976 to 1983 and a decrease afterwards. Neonatal characteristics independently associated with epilepsy were the presence of a brain malformation or a syndrome, a term or moderately preterm birth compared with a very premature birth, and signs of perinatal distress including neonatal seizures, neonatal ventilation and admission to a neonatal care unit. Conclusions: The prevalence of CP with epilepsy followed a quadratic trend in 1976e1998 and mirrored that of the prevalence of CP during this period. The observed relationship between epilepsy and associated impairments was expected; however it requires longitudinal studies to be better understood.
URI: http://hdl.handle.net/10400.17/876
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