Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.17/631
Título: Defeitos do Tubo Neural. Experiência de 10 Anos numa Maternidade Central
Outros títulos: Neural Tube Defects. The 10-Year Experience of a Central Maternity Hospital
Autor: Teixeira, AL
Loreto, H
Machado, MC
Ramos de Almeida, JM
Palavras-chave: Doenças Fetais
Maternidade Dr. Alfredo da Costa
Estatística
Defeitos do Tubo Neural
Portugal
Gravidez
Diagnóstico Pré-Natal
Prevalência
Estudos Retrospectivos
MAC PED
Data: 1994
Editora: Centro Editor e Livreiro da Ordem dos Médicos
Citação: Acta Med Port. 1994 Jul-Aug;7(7-8):419-25
Resumo: OBJECTIVES: 1) To determine trends in prevalence of neural tube defects and the impact of therapeutic abortion. 2) To review perinatal management of spina bifida. DESIGN: All spontaneous and therapeutic abortions, still births and live births affected by neural tube defects registered in Alfredo da Costa Maternity in Lisbon, from 1983 to 1992, were retrospectively analysed. RESULTS: Eighty-two cases with neural tube defects are reported and myelomeningocele and anencephaly++ were the most frequent ones. Total prevalence for all defects was 0.78:1000 births with a small upward trend during the last two years. Birth prevalence was 0.6:1000, with a clear downward trend, due to therapeutic abortion. Prenatal diagnosis improved significantly, from 9% of all defects detected in 1983-87 to 77.5% in 1988-92. Since 1989, all cases of anencephaly were detected before birth. Most cases of spina bifida were vaginally delivered, and elective cesarean section occurred in 4. Early closure of the defect was undertaken in 87.6% of the newborns with open spina bifida. CONCLUSION: While total prevalence of neural tube defects remained stable, with only a small upward trend, prenatal diagnosis and therapeutic abortion resulted in a 56.3% fall in birth prevalence. Optimal management of open spina bifida demands a multidisciplinary team with an individual program for each case.
Peer review: yes
URI: http://hdl.handle.net/10400.17/631
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