Please use this identifier to cite or link to this item: http://hdl.handle.net/10400.17/3093
Title: Maternal Educational Level and the Risk of Persistent Post-Partum Glucose Metabolism Disorders in Women with Gestational Diabetes Mellitus
Author: Gante, I
Ferreira, AC
Pestana, G
Pires, D
Amaral, N
Dores, J
Almeida, MC
Sandoval, JL
Keywords: Adult
Blood Glucose
Cohort Studies
Diabetes Mellitus, Type 2
Diabetes, Gestational
Female
Glucose Intolerance
Glucose Metabolism Disorders
Glucose Tolerance Test
Humans
Portugal
Postpartum Period
Pregnancy
Prevalence
Puerperal Disorders
Retrospective Studies
Risk Factors
Young Adult
Educational Status
Mothers
HCC NEF
Issue Date: Mar-2018
Publisher: Springer
Citation: Acta Diabetol. 2018 Mar;55(3):243-251.
Abstract: AIMS: Gestational diabetes mellitus (GDM) occurs in 5-15% of pregnancies, and lower maternal educational attainment has been associated with higher risk of GDM. We aimed to determine if maternal education level is associated with persistent post-partum glucose metabolism disorders in women with GDM. METHODS: Retrospective cohort study of women with GDM followed in 25 Portuguese health institutions between 2008 and 2012. Educational attainment was categorised into four levels. Prevalence of post-partum glucose metabolism disorders (type 2 diabetes mellitus, increased fasting plasma glucose or impaired glucose tolerance) was compared and adjusted odds ratios calculated controlling for confounders using logistic regression. RESULTS: We included 4490 women diagnosed with GDM. Educational level ranged as follows: 6.8% (n = 307) were at level 1 (≤ 6th grade), 34.6% (n = 1554) at level 2 (6-9th grade), 30.4% (n = 1364) at level 3 (10-12th grade) and 28.2% (n = 1265) at level 4 (≥ university degree). At 6 weeks post-partum re-evaluation, 10.9% (n = 491) had persistent glucose metabolism disorders. Educational levels 1 and 2 had a higher probability of persistent post-partum glucose metabolism disorders when compared to level 4 (OR = 2.37 [1.69;3.32], p < 0.001 and OR = 1.39 [1.09;1.76], p = 0.008, for level 1 and 2, respectively), an association that persisted in multivariable logistic regression adjusting for confounders (level 1 OR = 2.25 [1.53;3.33], p < 0.001; level 2 OR = 1.43 [1.09;1.89], p = 0.01). CONCLUSIONS: Persistent post-partum glucose metabolism disorders are frequent in women with GDM and associated with lower maternal educational level. Interventions aimed at this risk group may contribute towards a decrease in prevalence of post-partum glucose metabolism disorders.
Peer review: yes
URI: http://hdl.handle.net/10400.17/3093
DOI: 10.1007/s00592-017-1090-y
Appears in Collections:NEF - Artigos

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