Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.17/2844
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dc.contributor.authorCunha, JP-
dc.contributor.authorProença, R-
dc.contributor.authorDias-Santos, A-
dc.contributor.authorMelancia, D-
dc.contributor.authorAlmeida, R-
dc.contributor.authorÁguas, H-
dc.contributor.authorOliveira Santos, B-
dc.contributor.authorAlves, M-
dc.contributor.authorFerreira, J-
dc.contributor.authorPapoila, AL-
dc.contributor.authorLouro, C-
dc.contributor.authorCastanheira-Dinis, A-
dc.date.accessioned2018-01-09T16:48:50Z-
dc.date.available2018-01-09T16:48:50Z-
dc.date.issued2017-
dc.identifier.citationAlzheimers Dement (Amst). 2017 Mar 30;8:11-17.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/2844-
dc.description.abstractINTRODUCTION: The purpose of this study was to measure and to compare macular choroidal thickness (CT) between patients with mild Alzheimer's disease (AD), patients without AD, and elderly patients. METHODS: CT was measured manually in 13 locations at 500-μm intervals of a horizontal and a vertical section from the fovea. Linear regression models were used to analyze the data. RESULTS: Fifty patients with a diagnosis of mild AD (73.1 years), 152 patients without AD (71.03 years), and 50 elderly without AD (82.14 years) were included. In the AD patients, CT was significantly thinner in all 13 locations (P < .001-comparing with age-match group), and comparing with the elderly group, a more pronounced difference was found in two locations temporal to the fovea. DISCUSSION: Patients with AD showed a significant choroidal thinning even when compared with elderly subjects. The reduction of CT may aid in the diagnoses of AD, probably reflecting the importance of vascular factors in their pathogenesis.pt_PT
dc.language.isoengpt_PT
dc.publisherElsevierpt_PT
dc.rightsopenAccesspt_PT
dc.subjectCHLC OFTpt_PT
dc.subjectCHLC CINVpt_PT
dc.subjectCHLC NEUpt_PT
dc.subjectAlzheimer's Choroidopathypt_PT
dc.subjectAlzheimer's Diseasept_PT
dc.subjectChoroidal Thicknesspt_PT
dc.subjectEnhanced Depth Imagingpt_PT
dc.subjectSpectral-Domain Optical Coherence Tomographypt_PT
dc.titleChoroidal Thinning: Alzheimer's Disease and Agingpt_PT
dc.typearticlept_PT
dc.peerreviewedyespt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
degois.publication.firstPage11pt_PT
degois.publication.lastPage17pt_PT
degois.publication.titleAlzheimer's & Dementiapt_PT
degois.publication.volume8pt_PT
dc.identifier.doi10.1016/j.dadm.2017.03.004pt_PT
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OFT - Artigos
CINV - Artigos

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