Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.17/276
Título: Valor Prognóstico da Normalização da Resposta Ventilatória ao Exercício para o Consumo Máximo de Oxigénio na Insuficiência Cardíaca
Outros títulos: Combining Ventilatory Efficiency and Peak Oxygen Consumption in the Prognostic Assessment of Patients with Chronic Heart Failure
Autor: Toste, A
Soares, RM
Feliciano, J
Andreozzi, V
Silva, S
Alves, S
Ferreira, ML
Abreu, A
Cruz Ferreira, R
Palavras-chave: Doença Crónica
Prova de Esforço
Insuficiência Cardíaca
Consumo de Oxigénio
Prognóstico
Estudos Prospectivos
Data: 2010
Editora: Sociedade Portuguesa de Cardiologia
Citação: Rev Port Cardiol. 2010 Sep;29(9):1305-20
Resumo: Cardiopulmonary exercise testing (CPET) is an objective method for assessment of functional capacity and for prognostic stratification of patients with chronic heart failure (CHF). In this study, we analyzed the prognostic value of a recently described CPET-derived parameter, the minute ventilation to carbon dioxide production slope normalized for peak oxygen consumption (VE/VCO2 slope/pVO2). METHODS: We prospectively studied 157 patients with stable CHF and dilated cardiomyopathy who performed maximal CPET using the modified Bruce protocol. The prognostic value of VE/VCO2 slope/pVO2 was determined and compared with traditional CPET parameters. RESULTS: During follow-up 37 patients died and 12 were transplanted. Mean follow-up in surviving patients was 29.7 months (12-36). Cox multivariate analysis revealed that VE/VCO2 slope/pVO2 had the greatest prognostic power of all the parameters studied. A VE/VCO2 slope/pVO2 of > or = 2.2 signaled cases at higher risk. CONCLUSION: Normalization of the ventilatory response to exercise for peak oxygen consumption appears to increase the prognostic value of CPET in patients with CHF.
Peer review: yes
URI: http://hdl.handle.net/10400.17/276
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