Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.17/2394
Título: Autism Spectrum Disorder Secondary to Enterovirus Encephalitis
Autor: Marques, F
Brito, MJ
Conde, M
Pinto, M
Moreira, A
Palavras-chave: Brain/pathology
Brain/radionuclide imaging
Child Development Disorders, Pervasive/etiology
Encephalitis, Viral/complications
Encephalitis, Viral/etiology
Enterovirus Infections/complications
Magnetic Resonance Imaging
Tomography, Emission-Computed, Single-Photon
Child, Preschool
Case Reports
HDE INF PED
HDE NEU PED
HDE CDPED
Data: Mai-2014
Editora: Sage Publications
Citação: J Child Neurol. 2014, Vol. 29(5) 708-714
Resumo: Millions of children are infected by enteroviruses each year, usually exhibiting only mild symptoms. Nevertheless, these viruses are also associated with severe and life-threatening infections, such as meningitis and encephalitis. We describe a 32-month-old patient with enteroviral encephalitis confirmed by polymerase chain reaction in cerebrospinal fluid, with unfavorable clinical course with marked developmental regression, autistic features, persistent stereotypes and aphasia. She experienced slow clinical improvement, with mild residual neurologic and developmental deficits at follow-up. Viral central nervous system infections in early childhood have been associated with autism spectrum disorders but the underlying mechanisms are still poorly understood. This case report is significant in presenting a case of developmental regression with autistic features and loss of language improving on follow-up. To our knowledge, this is the first published report of enterovirus encephalitis leading to an autism spectrum disorder.
URI: http://hdl.handle.net/10400.17/2394
DOI: 10.1177/0883073813508314
Aparece nas colecções:NEU PED - Artigos
INF PED - Artigos
CDPED - Artigos

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