Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.17/2241
Título: Warm Antibody Autoimmune Haemolytic Anaemia Associated with Ovarian Teratoma
Autor: Raimundo, P
Coelho, S
Cabeleira, A
Dias, L
Gonçalves, M
Palavras-chave: HSJ MED
Anemia, Hemolytic, Autoimmune/immunology
Coombs Test
Diagnosis, Differential
Ovarian Neoplasms/diagnosis
Ovarian Neoplasms/immunology
Ovarian Neoplasms/surgery
Tomography, X-Ray Computed
Data: 2010
Editora: BMJ Publishing Group
Citação: BMJ Case Rep. 2010 May 19;2010. pii: bcr0620091971
Resumo: The ovarian cystic teratoma is a rare cause of autoimmune haemolytic anaemia by warm antibodies, resistant to corticotherapy, with few case reports published in the medical literature. We present a case of a 45-year-old woman admitted to hospital due to general weakness. Laboratory studies revealed macrocytic anaemia, biochemical parameters of haemolysis and peripheral spherocytosis. The direct Coombs test was positive. Viral serologies, anti-nuclear antibodies, anti-double-stranded DNA antibodies and β2-microglobulin were negative. CT scan of the thorax, abdomen and pelvis showed a heterogeneous right anexial lesion. The patient was treated with corticotherapy without improvement of anaemia. Regression of extra-vascular haemolysis and normalisation of haemoglobin was obtained only after laparoscopic splenectomy and right ooforectomy, and the histopathology of the right anexial mass revealed a cystic teratoma. Previously published cases controlled the haemolysis by surgically removing the lesion associated with splenectomy.
Peer review: yes
URI: http://hdl.handle.net/10400.17/2241
Aparece nas colecções:CIR - Artigos
MED - Artigos
ANPAT - Artigos

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