Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.17/1946
Título: The Role of Prostaglandins in the Lower Urinary Tract Dynamics of Prostatectomized Patients: a Trial with Indomethacin and Aspirin
Outros títulos: O Papel das Prostaglandinas na Dinâmica do Tracto Urinário Inferior de Doentes Prostatectomizados: um Ensaio com Indometacina e Aspirina
Autor: Matos Ferreira, A
Reis Santos, JM
Palavras-chave: HCC URO
Aspirin
Indomethacin
Prostaglandins
Prostatectomy
Urinary Tract
Urodynamics
Data: 1983
Editora: Centro Editor e Livreiro da Ordem dos Médicos
Citação: Acta Med Port. 1983 Jan;4(1):21-33.
Resumo: Using 49 prostatectomized patients as experimental subjects, we studied the effects of Inclometnacin and acetylsalicylic acid — accredited prostaglandin synthetase inhibitors — from a urodynamic and clinical standpoint. Relevant urodynamic data was gathered 1 hr 30 mi after the patients had taken the drugs and placebo. Clinical results were further scrutinized after 8 days of treatment, at which time a new urodynamic workup was again performed on some patients. Results were again studied shortly after the end of treatment. The effect of the drugs on bladder and urethral structures was borne out by clear-ct!t clinical and urodynamic changes. After statistically analyzing such changes, we concluded that prostaglandin synthesis inhibition resulting in the inhibition of prostaglandin action had, at least in part, led to the changes noted. In the present report we shall discuss the role played by the highly complex mechanisms at work.
Peer review: yes
URI: http://hdl.handle.net/10400.17/1946
Aparece nas colecções:URO - Artigos

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