Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.17/1797
Título: Personality, Brain Asymmetry, and Neuroendocrine Reactivity in Two Immune-Mediated Disorders: a Preliminary Report
Autor: Martin Martins, J
Alves, J
Trinca, A
Grima, B
Vale, S
Vasconcelos, T
Riso, N
Vaz Riscado, M
Charneco da Costa, J
Palavras-chave: HCC END
Hormona Adrenocorticotrópica
Sulfato de Desidroepiandrosterona
Lateralidade Funcional
Cérebro
Hepatite C
Hidrocortisona
Lúpus Eritematoso Sistémico
MMPI
Sistemas Neurossecretores
Personalidade
Projectos Piloto
Prolactina
Data: 2002
Editora: Elsevier
Citação: Brain Behav Immun. 2002 Aug;16(4):383-97
Resumo: Development of some immune-mediated disorders may depend on dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis. To explore neuropsychologic mechanisms in relation to the abnormal endocrine reactivity in patients with systemic lupus erythematosus (SLE) and chronic hepatitis C (CHC) we used the corticotropin releasing hormone (CRH) test, the Minnesota Multiphasic Personality Inventory (MMPI), and the Edinburgh Inventory of Manual Preference Inventory (EIMP). Compared to controls, the adrenocorticotrophic hormone (ACTH) response to CRH was reduced in CHC, while SLE presented reduced baseline dehydroepiandrosterone sulfate levels; higher neurotic scores were found in SLE and higher behavior deviant scores in CHC. Peak ACTH levels were a significant factor for the MMPI profile variability, while the manual preference score was a significant factor for the ACTH response. Personality and manual preference contribute to neuroendocrine abnormalities. Different behavioral and neuroimmunoendocrine models emerge for these disorders.
Peer review: yes
URI: http://hdl.handle.net/10400.17/1797
Aparece nas colecções:END - Artigos

Ficheiros deste registo:
Ficheiro Descrição TamanhoFormato 
BBI 2002 383.pdf106,25 kBAdobe PDFVer/Abrir


FacebookTwitterDeliciousLinkedInDiggGoogle BookmarksMySpace
Formato BibTex MendeleyEndnote Degois 

Todos os registos no repositório estão protegidos por leis de copyright, com todos os direitos reservados.