Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.17/1470
Título: Phototherapy in Childhood: a 17-Year Retrospective Study Regarding Effectiveness and Safety
Autor: Brasileiro, A
Campos, S
Páris, F
Fidalgo, A
Apetato, M
Palavras-chave: Fototerapia
Estudos Retrospectivos
Data: 2013
Editora: Serviço de Dermatologia do Hospital dos Capuchos, Centro Hospitalar de Lisboa Central, EPE
Citação: IN: 12th World Congress of Pediatric Dermatology; 2013, 25 a 27 Set. Madrid, Espanha
Resumo: Introduction: Skin diseases in paediatric age are often distressing conditions with significant impact in children’s psychosocial development. Additionally, systemic therapeutic options are often limited in childhood, due to its potential toxicity in this vulnerable group. Phototherapy is therefore an endorsed option for photo-responsive dermatological conditions. Objective and Methods:This observational retrospective study aims to access efficacy and safety of Phototherapy in our paediatric population. Relevant clinical data from 1996 to present concerning patients aged 18 years or less was collected. Results: 78 patients were included, of which64,1%was female. Mean age was 12,9 years (range 2-18). Distribution according to diagnosis was:47,4%psoriasis, 34,6% alopecia areata, 9,0% vitiligo, 9,0% other diagnosis. Mean number of cycles was 1,5 (range 1-7), with an average of 16,3 treatments per cycle and mean cumulative dose 134 J/cm2. 70,5% was treated with one single cycle. Topic and systemic PUVA were the first choice in 37,2% and 39,7%, respectively, while UVB TL01 and broadband UVB were used in 11,5% each. On the first cycle 67,5% improved, 14,3% showed no sustained clinical response and 19,5% were lost to follow-up. Psoriasis patients had the best response rates (81,8%), followed by alopecia areata (59,3%). Side effects occurred in 21%, being erythema the most common (12%). None led to therapeutic interruption. Discussion: Phototherapy is a safe and effective option in childhood, yet the withdraw rate might be an important limitation.
Peer review: yes
URI: http://hdl.handle.net/10400.17/1470
Aparece nas colecções:DER - Comunicações e Conferências

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