Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.17/1330
Título: Tamoxifeno e Espessamento Endometrial Assintomático
Outros títulos: Tamoxifen and Assymptomatic Endometrial Thickness
Autor: Amaral, N
Robalo, R
Fatela, A
Palavras-chave: Tamoxifeno
Estudos Retrospectivos
Diagnóstico
Data: 2008
Editora: Sociedades Portuguesas de Obstetrícia e Ginecologia
Citação: Acta Obstet Ginecol Port 2008;2(2):80-83
Resumo: Tamoxifen is a first-line agent for adjuvant treatment of estrogen-receptor positive breast cancer, and is used to reduce the risk of this condition in high-risk individuals. Retrospective studies established an association between tamoxifen use, endometrial thickness and endometrial cancer. There have been many attempts to identify an effective screening program for tamoxifen-related endometrial cancer, which have led to the use of transvaginal ultrasound and invasive procedures. The use of a 5mm endometrial cut-off in vaginal ultrasound is known to raise the number of endometrial biopsies with no gain in early cancer diagnosis. A review of the scientific literature was performed in order to establish the best available evidence for endometrial evaluation of asymptomatic breast cancer patients on tamoxifen.
Peer review: yes
URI: http://hdl.handle.net/10400.17/1330
Aparece nas colecções:GIN - Artigos

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