Utilize este identificador para referenciar este registo: http://hdl.handle.net/10400.17/1023
Título: De Novo Hypertension and Decline of Renal Function in a Young Woman with Systemic Lupus Erythematosus and Antiphospholipid Syndrome
Autor: Viana, H
Ferreira, A
Carvalho, F
Bordalo, J
Ribeiro Santos, J
Palavras-chave: Síndrome Antifosfolipídico
Biópsia
Hipertensão
Lúpus Eritematoso Sistémico
Data: 2009
Editora: Sociedade Portuguesa de Nefrologia e Hipertensão
Citação: Port J Nephrol Hypert 2009; 23 (4): 357-361
Resumo: Antiphospholipid syndrome nephropathy and lupus nephritis have similar clinical and laboratory manifestations and achieving the accuracy of diagnosis required for correct treatment frequently necessitates a kidney biopsy. We report the case of a 29-year-old woman referred to the nephrology service for de novo hypertension, decline of renal function and proteinuria. She had had systemic lupus erythematosus and antiphospholipid syndrome since the age of 21 and was taking oral anticoagulation. Two weeks later, after treatment of hypertension and achievement of adequate coagulation parameters, a percutaneous renal biopsy was performed. The biopsy revealed chronic lesions of focal cortical atrophy, arterial fibrous intimal hyperplasia and arterial thromboses, which are typical features of antiphospholipid syndrome nephropathy. We describe the clinical manifestations and histopathology of antiphospholipid syndrome nephropathy and review the literature on renal biopsy in patients receiving anticoagulation.
Peer review: yes
URI: http://hdl.handle.net/10400.17/1023
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